Yes you definitely don't want to be breathing in resin dust - it'll burn your nostrils. Always wash your hands after handling resin and work outside if possible.
Only use superglue for assembly as regular styrene glue won't touch it.
The advantages of resin are that any bodywork or filler that you apply tends to go on smoother and not leave ghost lines behind like regular plastic.
Also you can use pretty much any type of paint on resin without a problem. Just make sure the resin is cleaned of all mould releases agents and grease from your skin.
Mike